Post Doc

Postdoctoral RA Position in the US: University of Connecticut- USA

November 4, 2020

Designation/Position- Postdoctoral RA Position in US

University of Connecticut, United States invites application for Postdoctoral RA Position in US from eligible and interested candidates

About- The University of Connecticut is a public research university in Storrs, Connecticut. It was founded in 1881. The primary 4,400-acre campus is in Storrs, Connecticut, approximately a half hour’s drive from Hartford and 90 minutes from Boston. Postdoctoral RA Position in US

Research/Job Area- Biology, Genetics, Immunology, or closely related field

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Location- Storrs Campus, US

Eligibility/Qualification–

MINIMUM QUALIFICATIONS

PhD in evolutionary biology, genetics, immunology, or a closely related field Prior experience with molecular genetics or immunology.

PREFERRED QUALIFICATIONS

Previous research experience and publications should demonstrate a commitment to basic research, good work ethic, lab skills, organizational ability, and publication productivity.
Expertise in CRISPR/cas9 gene editing.

Job/Position Description-

JOB SUMMARY

A Postdoctoral Research Associate position is available in Dr. Daniel Bolnick’s research group (https://bolnicklab.wordpress.com), in the Department of Ecology and Evolution at the University of Connecticut. The postdoc will join an ongoing NIH-funded project to use CRISPR/cas9 gene editing of threespine stickleback to evaluate the phenotypic effect of candidate genes on host immune phenotypes and resistance to cestode infection. The postdoc may also begin work on a related question of how cestode genotype affects infection outcome and host phenotypes.

DUTIES AND RESPONSIBILITIES

The Postdoctoral Research Associate will combine experimental genetics with immune challenges to identify the genetic and immunological basis of rapidly-evolved population differences in stickleback immunity to a cestode parasite, and associated costly immunopathology. The Bolnick lab has identified naturally evolved heritable differences in stickleback fishes’ ability to resist infection, and suppress growth of established cestodes. This resistance entails a recently-evolved fibrosis immune response that can be experimentally studied using an artificial vaccination strategy (see https://bolnicklab.wordpress.com/2015/10/12/bolnick-lab-publications/ for recent publications concerning evolution of cestode resistance and fibrosis). Using QTL mapping, GWAS, population genomic divergence, and transcriptomics we have identified promising candidate genes potentially underlying these immunological differences. With funding from the NIH, we have successfully implemented RISPR/cas9 gene editing of some candidate genes. The postdoc hired for this position will extend this gene editing work to encompass more replicates, more candidate genes, and evaluate the phenotypic effect of these transgenic manipulations using experimental infections and artificial vaccination assays. The work will be based at the University of Connecticut, though some field work may be necessary, such as to breed fish for lab work or to obtain cestodes. The postdoc will be responsible for conducting lab and field work, co-supervising laboratory technicians and students, data analysis and publication. Opportunities exist to pursue side-projects along with the core project task.

How to Apply-

Please apply online at https://hr.uconn.edu/jobs, Staff Positions, Search #494822. Applications should electronically submit a single pdf file containing the following, in order:

A statement of past research achievements, including relevant skills (1-2 pages)
A statement of what you can contribute to the Bolnick Lab’s research, and how this fits into your career goals. This should not exceed one single-spaced page.
A CV
A copy of two publications or submitted manuscripts.
A list of three references, with contact information (email, telephone, and mailing address). We will request letters directly from these references, after identifying top candidates.

An initial application should be emailed to Dr. Daniel Bolnick (daniel.bolnick@uconn.edu). For full consideration applicants will also need to apply via UConn Jobs. Include the subject line “Evolutionary immune genetics Postdoc: “. Application review will begin on December 1, 2020, though late applications will be accepted until the position is filled.

Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check.

This job posting is scheduled to be removed at 11:55 p.m. Eastern time on December 8, 2020.

All employees are subject to adherence to the State Code of Ethics which may be found t http://www.ct.gov/ethics/site/default.asp.