Designation/Position- Research-Associate at IIT Madras
IIT Madras, India invites applications for Research-Associate at IIT Madras from eligible and interested candidates.
About- Applications are invited for the temporary post of Research Associate – I, Department of Mathematics, IIT Madras.
Research/Job Area-Â Science, Engineering, Physics, Biophysics, Computational Biology, or a related discipline
Location- IIT Madras, India
Eligibility/Qualification–
| Ph.D. in Science, Engineering, Physics, Biophysics, Computational Biology, or a related discipline. Experience in molecular dynamics simulations of DNA, RNA, or related biomolecular systems. Strong programming skills in Python/MATLAB, with experience in high-performance computing. Background in nucleic acid biophysics, computational biology, statistical mechanics, soft matter physics. Experience in coarse-grained modelling, AI/ML methods, scientific computing, and data analysis. |
Job/Position Description-
Applications are invited for the temporary post of Research Associate – I, Department of Mechanical Engineering, IIT Madras.
Co-ordinators: Dr. Raushan Singh, Department of Mechanical Engineering, IIT Madras
Prof. Narasimhan Swaminathan, Department of Mechanical Engineering, IIT Madras
Prof. Athi Narayanan Naganathan, Department of Biotechnology, IIT Madras
Duration: Initially for one year, later extendable (up to total three years) based on the performance. Number of Vacancies: 01
| Post | Pay |
| Research Associate-I | ₹58,000 per month + 30% HRA [Total Consolidated Pay: ₹75,400 per month]. |
Job Description:
- Develop computational models to investigate sequence-dependent mechanical properties of DNA, RNA, DNA–RNA hybrids and chemically modified nucleic acids under external mechanical loading (e.g., force and torque).
- Perform coarse-grained simulations, molecular dynamics simulations (using AMBER), and Monte Carlo/statistical sampling studies for model development, validation, and analysis.
- Develop high-throughput computational workflows using Python/C++, and HPC resources to simulate and analyse large-scale nucleic acid sequence datasets.
- Construct and analyse genome-scale mechanical atlases by quantifying sequence-dependent properties such as stiffness, flexibility, bendability, and other mechanical properties.
- Investigate the effects of sequence variations, single-nucleotide mutations, and epigenetic modifications on nucleic acid mechanics and their potential biological implications.
- Perform data-driven analyses, motif discovery, and AI/ML-based approaches, to identify mechanically significant sequence patterns and signatures.
- Integrate mechanical predictions with genomic and functional datasets to support genome annotation, variant prioritization, and studies of gene regulation.
- Develop, document, and maintain scientific software and computational tools for dissemination to the broader research community.
- Contribute to project reports, research publications, presentations, student mentoring, and collaborative research activities.
How to Apply-
Candidates should apply online only in the website https://icandsr.iitm.ac.in/careers/current_openings.php – (Please check the advertisement number Advt.120/2026 displayed and submit the application for the relevant position).
Last Date for Apply– 08 July 2026
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